diff --git a/wrap/cmake/MatlabWrap.cmake b/wrap/cmake/MatlabWrap.cmake
index c45d8c050..55b7cdb99 100644
--- a/wrap/cmake/MatlabWrap.cmake
+++ b/wrap/cmake/MatlabWrap.cmake
@@ -105,7 +105,12 @@ function(wrap_library_internal interfaceHeader moduleName linkLibraries extraInc
       set(mexModuleExt mexglx)
     endif()
   elseif(APPLE)
-    set(mexModuleExt mexmaci64)
+    check_cxx_compiler_flag("-arch arm64" arm64Supported)
+    if (arm64Supported)
+      set(mexModuleExt mexmaca64)
+    else()
+      set(mexModuleExt mexmaci64)
+    endif()
   elseif(MSVC)
     if(CMAKE_CL_64)
       set(mexModuleExt mexw64)
@@ -299,7 +304,12 @@ function(wrap_library_internal interfaceHeader moduleName linkLibraries extraInc
       APPEND
       PROPERTY COMPILE_FLAGS "/bigobj")
   elseif(APPLE)
-    set(mxLibPath "${MATLAB_ROOT}/bin/maci64")
+    check_cxx_compiler_flag("-arch arm64" arm64Supported)
+    if (arm64Supported)
+      set(mxLibPath "${MATLAB_ROOT}/bin/maca64")
+    else()
+      set(mxLibPath "${MATLAB_ROOT}/bin/maci64")
+    endif()
     target_link_libraries(
       ${moduleName}_matlab_wrapper "${mxLibPath}/libmex.dylib"
       "${mxLibPath}/libmx.dylib" "${mxLibPath}/libmat.dylib")
@@ -367,7 +377,12 @@ function(check_conflicting_libraries_internal libraries)
   if(UNIX)
     # Set path for matlab's built-in libraries
     if(APPLE)
-      set(mxLibPath "${MATLAB_ROOT}/bin/maci64")
+      check_cxx_compiler_flag("-arch arm64" arm64Supported)
+      if (arm64Supported)
+        set(mxLibPath "${MATLAB_ROOT}/bin/maca64")
+      else()
+        set(mxLibPath "${MATLAB_ROOT}/bin/maci64")
+      endif()
     else()
       if(CMAKE_CL_64)
         set(mxLibPath "${MATLAB_ROOT}/bin/glnxa64")